Piroxicam Loaded Solid Lipid Nanoparticles (SLNs): Potential for Topical Delivery

Safranal-loaded solid lipid nanoparticles: evaluation of sunscreen and moisturizing potential for topical applications

Objective(s): In the current study, sunscreen and moisturizing properties of solid lipid nanoparticle (SLN)-safranal formulations were evaluated. Materials and Methods:Series of SLN were prepared using glyceryl monostearate, Tween 80 and different amounts of safranal by high shear homogenization, and ultrasound and high-pressure homogenization (HPH) methods. SLN formulations were characterized ...

safranal-loaded solid lipid nanoparticles: evaluation of sunscreen and moisturizing potential for topical applications

objective(s): in the current study, sunscreen and moisturizing properties of solid lipid nanoparticle (sln)-safranal formulations were evaluated. materials and methods:series of sln were prepared using glyceryl monostearate, tween 80 and different amounts of safranal by high shear homogenization, and ultrasound and high-pressure homogenization (hph) methods. sln formulations were characterized ...

preparation and assessment of piroxicam loaded solid lipid nanoparticles

Zaltoprofen Loaded Solid Lipid Nanoparticles for Topical Delivery: Formulation Design, In Vitro and Ex Vivo Evaluation

The number of new pharmaceutical compounds with poor aqueous solubility has grown steadily over the last two decades due to the progress in discovery technologies, e.g. high throughput and combinatorial screening tools, during lead development and optimization phase. Most of these compounds are mainly categorized as bio pharmaceutics classification system (BCS) class II for which their oral abs...

Temperature-Induced Release of All-trans-Retinoic Acid Loaded in Solid Lipid Nanoparticles for Topical Delivery

The aim of this work was to develop and evaluate solid lipid nanoparticles (SLN) containing all-transretinoic acid (ATRA) for topical delivery. SLN composed of coconut oil and curdlan improved the suspension instability of ATRA in aqueous solution. The photodegradation of ATRA by light was reduced by incorporation in SLN. The loading efficiency of ATRA in SLN was higher than 95% (w/w). The amou...